6 Deaf Children Can Now Hear After a Single Injection

[ To get the new genetic material into cells, they engineered harmless viruses to carry it. Doctors carefully injected a tiny amount of liquid containing the viruses into a part of the children’s inner ears called the cochlea, a spiral-shaped chamber that contains hair cells. The first patient in the trial received the gene therapy … Read more

FDA to require new warning of secondary cancer risk for CAR-T cancer therapies

[ The Food and Drug Administration (FDA) is requiring a boxed warning on all existing CAR-T cancer treatments following a review of reports that the therapies themselves can increase the risk for some secondary cancers.  In letters to the manufacturers of all six currently available CAR-T therapies dated Jan. 19, the FDA said the prescribing … Read more

In a World First, a Patient’s Antibody Cells Were Just Genetically Engineered

[ Our B cells help prevent us from getting sick. Their job is to make antibodies, immune system proteins that fight off viruses and other foreign invaders. And they make a lot of antibodies—thousands of them every second. What if these antibody factories could be harnessed to make other things the body needs? That’s the … Read more

A Cutting-Edge Cancer Treatment May Cause Cancer. The FDA Is Investigating

[ These therapies are made by adding genetic material to patients’ T cells in the lab, making them produce proteins on their surface called chimeric antigen receptors, or CARs. These CARS detect and bind to specific proteins on the surface of cancer cells, turning patients’ own cells into cancer assassins. Scientists use harmless viruses to … Read more