[ De-extinction startup Colossal Biosciences wants to bring back the woolly mammoth. Well, not the woolly mammoth exactly, but an Asian elephant gene-edited to give it the fuzzy hair and layer of blubber that allowed its close relative to thrive in sub-zero environments. To get to these so-called “functional mammoths,” Colossal’s scientists need to solve … Read more
[ To keep IL-12 inside tumors, scientists at Strand designed a set of instructions called a genetic circuit that tells the mRNA to make the inflammatory protein only when it detects the tumor microenvironment. The circuit is designed to sense levels of microRNA—molecules that naturally regulate gene expression and give off different signatures in cancer … Read more
[ Beijing-based ByteDance, which has been criticised in its home market for entering negotiations with American companies soon after US President Donald Trump ordered it to divest its operations in the US, emphasised on Monday that it will retain control over the new entity, TikTok Global. The Chinese entertainment giant said in a post on … Read more
[ Our B cells help prevent us from getting sick. Their job is to make antibodies, immune system proteins that fight off viruses and other foreign invaders. And they make a lot of antibodies—thousands of them every second. What if these antibody factories could be harnessed to make other things the body needs? That’s the … Read more
[ Casgevy uses the Nobel Prize–winning technology Crispr to modify patients’ cells so that they produce healthy hemoglobin instead. The Crispr system has two parts: a protein that cuts genetic material and a guide molecule that tells it where in the genome to make the cut. To do this, a patient’s stem cells are taken … Read more
